Mutia D. Hidayati, Arief Rahmatulloh
Uncaria Gambir is a popular plant in Southeast Asia, used traditionally for healing various diseases. Pharmacologically, U. Gambir has many potentials. This study aimed to investigate the antioxidant activities of U. Gambir stem extracts (methanol, ethyl acetate and n-hexane) using DPPH (2,2-diphenyl-2-2-picrylhydrazyl) and ABTS (2,2’-azinobis (3-ethylbenzothiazole-6-sulfonic acid) methods. The results of this study show that methanol extract has the highest antioxidant activity in the DPPH assay with IC50 value of 9.71 µg/mL. In addition, it has the highest ABTS activity with the IC50 value of 6.63 µg/mL. This study showed that the methanol extract of U. Gambir can potentially be used as an antioxidant. © 2022 Hidayati and Rahmatulloh.
Department of Chemical Engineering, Politeknik Negeri Malang, Malang, Indonesia